Another high-profile publication from our Department

   Our latest high-impact paper has been published in the prestigious Aging and Disease, the official journal of the International Society on Aging and Disease. The article, entitled “Senolytic treatment triggered by carotid occlusion confers protection against later acute ischemic stroke in aged rats”, is led by Dr. Szilvia V. Kecskés, Assistant Professor at our Department. In this study, we investigated whether the targeted removal of senescent cells accumulating in the walls of cerebral blood vessels could reduce stroke-induced brain damage in older age. Our results show that, under experimental conditions, the treatment reduced the size of cerebral infarcts and had beneficial effects on cerebral blood vessels as well as on age-related inflammatory and metabolic processes. These findings suggest that targeting the biological processes of aging may offer a new approach to increasing the resilience of the aging brain to stroke. Congratulations to all the authors on this excellent work!